secretion metabolism Isoprenoid metabolism Steroid metabolism Sterol metabolism Cholesterol metabolism M00104 Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
          M00107 Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone
          EPM0126 Cholesterol metabolism, cholesterol => choprostanol, cholestanol
          EPM0127 Cholesterol metabolism, cholesterol => 4-androstene-3,17-dione
          EPM0128 Cholesterol metabolism, cholesterol => 1,4-androstadeine-3,17-dione
      Bile acids metabolism (Secondary bile acids generation)   EPM0004 Cholic acid 7alpha-dehydroxylation
          EPM0130 Cholic acid metabolism, glycocholic acid => cholic acid => deoxycholic acid
          EPM0131 Cholic acid metabolism, glycocholic acid => cholic acid => allocholic acid
          EPM0132 Cholic acid metabolism, glycocholic acid => cholic acid => ethyl cholic acid
          EPM0133 Cholic acid metabolism, glycocholic acid => cholic acid => Bendigole F
          EPM0134 Cholic acid metabolism, glycocholic acid => cholic acid => 3-epicholic acid
          EPM0135 Cholic acid metabolism, glycocholic acid => cholic acid => 7-epicholic acid
          EPM0136 Cholic acid metabolism, glycocholic acid => cholic acid => 12-epicholic acid
      (Others)   M00103 Cholecalciferol biosynthesis
          M00106 Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate
          M00108 C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone
          M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
          M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
          EPM0110 Corticosterone transformation, corticosterone => 11beta-OH-3alpha,5alpha-TH-progesterone
    Terpenoid metabolism Triterpenoid metabolism   M00101 Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol
          EPM0105 Ginsenoside degradation, ginsenoside Rb1 => 20(S)-protopanaxadiol or 20(R)-protopanaxadiol
          EPM0106 Ginsenoside degradation, ginsenoside Rb1 => ginsenoside F2
  Others       M00029 Urea cycle
          EPM0043 urobilinoid production, bilirubin => urobilin
          EPM0090 Methylazoxymethanol-beta-glucuronide hydrolysis
Drug metabolism Isoprenoid metabolism Steroid metabolism Sterol metabolism   EPM0089 Ganoderol F metabolism, ganoderol F => ganodermatriol
    Terpenoid metabolism Triterpenoid metabolism   EPM0007 Glycyrrhizin Metabolism
          EPM0071 Glycyrrhizin metabolism, glycyrrhizin => 3alpha-hydroxyglycyrrhetic acid
          EPM0096 Saikosaponin b1 metabolism, saikosaponin b1 => saikogenin A
      Monoterpenoid metabolism Secoiridoid glycoside metabolism EPM0025 secoiridioid glycoside metabolism, swertiamarin => gentianine
          EPM0026 secoiridioid glycoside metabolism, swertiamarin => erythrocentaurin, 5-Hydroxymethylisochroman-1-one
          EPM0027 secoiridioid glycoside metabolism, gentiopicroside => gentiopicral
          EPM0028 secoiridioid glycoside metabolism, gentiopicroside => 5,6-dihydro-5-hydroxymethyl-6-methyl-1H,3H-pyrano[3,4-c]pyran-1-one
          EPM0029 secoiridioid glycoside metabolism, gentiopicroside => erythrocentaurin and others
          EPM0030 secoiridioid glycoside metabolism, sweroside => epinaucledal
          EPM0031 secoiridioid glycoside metabolism, sweroside => naucledal
        Iridoid glycoside metabolism EPM0032 iridoid glycoside metabolism, aucubin => aucubinine
          EPM0033 iridoid glycoside metabolism, geniposide => genipinine
          EPM0034 iridoid glycoside metabolism, gardenoside => gardenogenin
          EPM0035 iridoid glycoside metabolism, gardenoside => gardenine
        (Others) EPM0083 Paeoniflorin transformation, paeoniflorin => paeonimetabolin I (II, III and IV)
          EPM0084 Albiflorin metabolism, albiflorin => paeonilactone B
  Aromatic compounds metabolism Anthrone metabolism     EPM0069 Sennoside metabolism, sennoside A  (or B) => rheinanthrone
          EPM0077 Barbaloin metabolism, barbaloin => aloe-emodin anthrone
          EPM0095 Rhein metabolism, rhein => rheinanthrone
    Naphthoquinone metabolism     EPM0044 naphthoquinone metabolism, shikonin => shikometabolin E
          EPM0045 naphthoquinone metabolism, shikonin => shikometabolin A and B
          EPM0046 naphthoquinone metabolism, shikonin => shikometabolin C and D
          EPM0047 naphthoquinone metabolism, shikonin => cycloshikonin
    Isocoumarin metabolism     EPM0080 Bergenin transformation, bergenin =>  4-O-methylgallic acid
    Chromone metabolism     EPM0081 Aloesin metabolism, aloesin => (2'R)-aloesol 
          EPM0082 Aloeresin A  metabolism, aloeresin A => (2'S)-aloesol 
    Flavonoid metabolism Isoflavone metabolism   EPM0094 Flavonoid C-glucoside pathway, puerarin => daidzein
      Flavone metabolism   EPM0088 Baicalin metabolism, baicalin => baicalein
      (Others)   EPM0085 Abrusin 2''-O-beta-D-apioside degradation, abrusin 2''-O-beta-D-apioside => phenylpropionic acid, abrusin, dihydrocalcone derivative, denzenediol
    Phenylpropanoid metabolism Lignan metabolism   EPM0087 Arctiin transformation, arctiin => (-)-enterolactone
          EPM0093 Pinoresinol diglucoside transformation, pinoresinol diglucoside => (-)-(2R,3R)-enterolactone
          EPM0108 Trachelogenin degradation, (-)-trachelogenin => (-)-enterolactone
      Neolignan metabolism   EPM0091 Magnolol metabolism, magnolol => tetrahydromagnolol
      Diarylheptanoid metabolism   EPM0107 Curcumin degradation, curcumin => tetrahydrocurcumin
  Prontsil activation       EPM0066 Prontosil metabolism, prontosil => sulfanilamide
          EPM0067 Prontosil metabolism, neoprontosil => sulfanilamide
  Alkaloid metabolism       EPM0086 Aconitine metabolism, aconitine => lipoaconitine including bacterial fatty acid
  others       M00550 Ascorbate degradation, ascorbate => D-xylulose-5P
          EPM0013 picosulfate metabolism, picosulfate => dihydroxydiphenyl-pyridyl methane
          EPM0068 Salicylazo-sulfapyridine metabolism, salicylazo-sulfapyridine => sulfapyridin
          EPM0109 Safflor yellow B metabolism, safflor yellow B => hydroxysafflor yellow A + safflor-metabolin
food metabolism Isoprenoid metabolism Steroid metabolism Sterol metabolism   M00102 Ergocalciferol biosynthesis
          M00371 Castasterone biosynthesis, campesterol => castasterone
    Terpenoid metabolism Diterpenoid metabolism   M00097 beta-Carotene biosynthesis, GGAP => beta-carotene
          M00112 Tocopherol/tocotorienol biosynthesis
          EPM0020 Rebaudioside A degradation, rebaudioside A =>steviol
          EPM0021 Stevioside degradation, stevioside => steviol
      Carotenoid metabolism   M00372 Abscisic acid biosynthesis, beta-carotene => abscisic acid
    Isopentenyl diphosphate metabolism     M00364 C10-C20 isoprenoid biosynthesis, bacteria
          M00365 C10-C20 isoprenoid biosynthesis, archaea
          M00366 C10-C20 isoprenoid biosynthesis, plants
          M00367 C10-C20 isoprenoid biosynthesis, non-plant eukaryotes
  Aromatic compounds metabolism Tannin degradation     EPM0097 Urolithin B biosynthesis, ellagitannins => urolithin B
          EPM0116 Tannin degradation, ellagitannin -> pyruvate
          EPM0117 Tannin degradation, gallotannin -> pyruvate
    Xanthone metabolism     EPM0079 Mangiferin metabolism, mangiferin => 1,3,6,7-tetrahydroxyxanthone
    Catechol metabolism     M00568 Catechol ortho-cleavage, catechol => 3-oxoadipate
          M00569 Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
    Benzoate metabolism     M00540 Benzoate degradation, cyclohexanecarboxylic acid =>pimeloyl-CoA
          M00551 Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol
    Benzen metabolism     M00547 Benzene/toluene degradation, benzene => catechol / toluene => 3-methylcatechol
          M00548 Benzene degradation, benzene => catechol
    Toluene metabolism     M00418 Toluene degradation, anaerobic, toluene => benzoyl-CoA
          M00538 Toluene degradation, toluene => benzoate
          M00547 Benzene/toluene degradation, benzene => catechol / toluene => 3-methylcatechol
    Flavonoid metabolism Isoflavone metabolism   EPM0008 glycitein(Soy O-methylated isoflavone) demethylation
          EPM0073 Daidzin metabolism, daidzein => (S)-equil
          EPM0074 Daidzin metabolism, daidzin => O-Desmethylangolensin
          EPM0075 Genistein metabolism, genistin => p-ethylphenol or 6-hydroxy-O-desmethylangolensin
      Flavone metabolism   EPM0064 Flavonoid glycosides Hydrolysis, Rutin / Quercitrin => Quercetin
          EPM0078 Homoorientin metabolism, homoorientin => 3,4-dihydroxyphenylpropionic acid + phloroglucinol
          EPM0104 Quercetin metabolism, quercetin-3-glucoside => 3,4-dihydroxyphenylacetate + more
      Flavanone metabolism   M00138 Flavonoid biosynthesis, naringenin => pelargonidin
          EPM0120 Eriocitrin metabolism, eriocitrin -> flavonoid compounds
          EPM0098 Hesperetin 7-O-rutinoside catabolism, hesperetin 7-O-rutinoside => 3-hydroxyphenylhydracrylic acid
      Catechin metabolism   EPM0009 Catechin converting
          EPM0010 Epicatechin converting
      Anthocyanin metabolism   EPM0049 anthocyanin metabolism
          EPM0050 enocianin degradation
      (Others)   EPM0062 Neohesperidin dihydrochalcone metabolism, neohesperidin dihydrochalcone => 3,4-dihydroxyphenylpropionic acid
    Phenylpropanoid metabolism Lignan metabolism   EPM0057 mammalian lignan generation, secoisolariciresinol diglucoside => enterolactone
      Chlorogenic acid metabolism   EPM0111 Chlorogenic acids catabolism, 2-O-caffeoyltartaric acid -> benzoic acid
          EPM0112 Chlorogenic acids catabolism, 3-O-caffeoylquinic acid -> benzoic acid
          EPM0113 Chlorogenic acids catabolism, 5-O-caffeoylquinic acid -> benzoic acid
          EPM0114 Chlorogenic acids catabolism, 3-O-feruloylquinic acid -> 3-phenylpropionic acid
      Cinamate metabolism   M00039 Monolignol biosynthesis, phenylalanine/tyrosine  => monolignol
          M00545 Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA
      Coumarin metabolism   EPM0061 aesculin metabolism, aesculin => aesculetin
      (Others)   M00137 Flavanone biosynthesis, phenylalanine => naringenin
    (Others)     EPM0051 hydroxyphenylpropionate fermentation, hydroxyphenylpropionate => phenylpropionate
          M00419 Cymene degradation, p-cymene => p-cumate
          M00533 Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate
          M00534 Naphthalene degradation, naphthalene => salicylate
          M00537 Xylene degradation, xylene => methylbenzoate
          M00539 Cumate degradation, p-cumate => 2-oxopent-4-enoate + 2-methylpropanoate
          M00541 Benzoyl-CoA degradation, benzoyl-CoA => 3-hydroxypimeloyl-CoA
          M00543 Biphenyl degradation, biphenyl => 2-oxopent-4-enoate + benzoate
          M00544 Carbazole degradation, carbazole => 2-oxopent-4-enoate + anthranilate
  Amino acid metabolism Glycine metabolism     M00346 Formaldehyde assimilation, serine pathway
    Valine metabolism     M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate
    Leucine metabolism     M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA
    Methionine metabolism     M00034 Methionine salvage pathway
          M00035 Methionine degradation
          M00368 Ethylene biosynthesis, methionine => ethylene
    Phenylalanine metabolism     M00350 Capsaicin biosynthesis, L-Phenylalanine => Capsaicin
    Tryptophan metabolism     M00037 Melatonin biosynthesis, tryptophan => serotonin => melatonin
          M00038 Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate
          M00370 Glucosinolate biosynthesis, tryptophan => glucobrassicin
          EPM0039 tryptophan metabolism, tryptophan => indole
          EPM0048 tryptophan metabolism, tryptophan => 3-methylindole
    Serine metabolism     M00021 Cysteine biosynthesis, serine => cysteine
          M00338 Cysteine biosynthesis, homocysteine + serine => cysteine
    Threonine metabolism     M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
          M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
    Glutamine metabolism     M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP
          M00051 Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP
    Tyrosine metabolism     M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
          M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
          M00044 Tyrosine degradation, tyrosine => homogentisate
          M00369 Cyanogenic glycoside biosynthesis, tyrosine => dhurrin
          EPM0022 Tyrosine metabolism, tyrosine => 4-ethylphenol
          EPM0023 Tyrosine metabolism, tyrosine => 4-methylphenol
          EPM0024 Tyrosine metabolism, tyrosine => phenol
          EPM0041 tyrosine metabolism, tyrosine => p-cresol
    Lysine metabolism     M00032 Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
    Arginine metabolism     M00047 Creatine pathway
          M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine
          M00134 Polyamine biosynthesis, arginine => ornithine => putrescine
          EPM0063 polyamine biosynthesis, arginine => spermidine
    Histidine metabolism     M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate
          EPM0042 histidine metabolism, histidine => urocanic acid
    Glutamate metabolism     M00015 Proline biosynthesis, glutamate => proline
          M00027 GABA (gamma-Aminobutyrate) shunt
          M00028 Ornithine biosynthesis, glutamate => ornithine
          M00118 Glutathione biosynthesis, glutamate => glutathione
          M00121 Heme biosynthesis, glutamate => protoheme/siroheme
    Aspartate metabolism Lysine biosynthesis   M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
          M00525 Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine
          M00526 Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
          M00527 Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
      (Others)   M00017 Methionine biosynthesis, apartate => homoserine => methionine
          M00018 Threonine biosynthesis, aspartate => homoserine => threonine
          M00033 Ectoine biosynthesis, aspartate => ectoine
          M00115 NAD biosynthesis, aspartate => NAD
  Glycan metabolism Glycan catabolism Glycosaminoglycan metabolism   M00076 Dermatan sulfate degradation
          M00077 Chondroitin sulfate degradation
          M00078 Heparan sulfate degradation
          M00079 Keratan sulfate degradation
      (Others)   M00081 Pectin degradation
          EPM0017 Polysaccharide degradation, heparin =>
          EPM0018 Polysaccharide degradation, Laminarin => glucose higher oligomer
          EPM0019 Polysaccharide degradation, xylan => xylose
          EPM0103 Polysaccharide utilization, porphyran => disaccharide L6S–G
          EPM0124 Polysaccharide degradation, lactosucrose => SCFAs
          EPM0125 Polysaccharide degradation, arabinogalactan => SCFAs
    Glycan anabolism Glycosaminoglycan biosynthesis   M00057 Glycosaminoglycan biosynthesis, linkage tetrasaccharide
          M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone
          M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone
      Glycosphingolipid biosynthesis   M00068 Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer
          M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3
          M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer
          M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer
      (Others)   M00055 N-glycan precursor biosynthesis
          M00056 O-glycan biosynthesis, mucin type core
          M00065 GPI-anchor biosynthesis, core oligosaccharide
          M00073 N-glycan precursor trimming
          M00074 N-glycan biosynthesis, high-mannose type
          M00075 N-glycan biosynthesis, complex type
  Monosaccharide metabolism Glucose and derivatives metabolism Glucose 1P metabolism   M00129 Ascorbate biosynthesis, animals, glucose-1P => ascorbate
          M00565 Trehalose biosynthesis, D-glucose 1P => trehalose
      alpha-Glucose 6P metabolism   M00114 Ascorbate biosynthesis, plants, glucose-6P => ascorbate
      beta-Glucose 6P metabolism   M00004 Pentose phosphate pathway (Pentose phosphate cycle)
          M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P
          M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P
          M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate
      Glucronate metabolism   M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P
      Gluconate metabolism   M00308 Semi-phosphorylative Entner-Doudoroff pathway, gluconate => glycerate-3P
          M00309 Non-phosphorylative Entner-Doudoroff pathway, gluconate/galactonate => glycerate
      UDP-glucose metabolism   M00014 Glucuronate pathway (uronate pathway)
      UDP-glucosamine metabolism   M00060 Lipopolysaccharide biosynthesis, KDO2-lipid A
      (Others)   M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
          M00002 Glycolysis, core module involving three-carbon compounds
          M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose
    Galactose metabolism     M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose
    Ribose metabolism     M00005 PRPP biosynthesis, ribose 5P => PRPP
          M00026 Histidine biosynthesis, PRPP => histidine
          EPM0100 2-Deoxy-alpha-D-ribose 1-phosphate degradation, 2-deoxy-alpha-D-ribose 1-phosphate => acetyl-CoA  / D-glyceraldehyde 3-phosphate
    Arabinose metabolism     M00063 CMP-KDO biosynthesis
    Ribulose metabolism     M00165 Reductive pentose phosphate cycle (Calvin cycle)
          M00166 Reductive pentose phosphate cycle, ribulose-5P => glyceraldehyde-3P
          M00167 Reductive pentose phosphate cycle, glyceraldehyde-3P => ribulose-5P
          M00532 Photorespiration
    Erythrose metabolism     M00124 Pyridoxal biosynthesis, erythrose-4P => pyridoxal-5P
    Sedoheptulose metabolism     M00064 ADP-L-glycero-D-manno-heptose biosynthesis
    Glyceraldehyde and derivatives metabolism     M00020 Serine biosynthesis, glycerate-3P => serine
          M00089 Triacylglycerol biosynthesis
          M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway
          EPM0005 MEP pathway, isoprenoid biosynthesis
          EPM0101 2-O-alpha-mannosyl-D-glycerate degradation, 2-O-(6-phospho-alpha-D-mannosyl)-D-glycerate => D-mannose 6-phosphate + D-glycerate / 2-phospho-D-glycerate
  (Others)       M00003 Gluconeogenesis, oxaloacetate => fructose-6P
  Oxoglutarate metabolism       M00030 Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
          M00433 Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate
  (Others)       M00031 Lysine biosynthesis, 2-aminoadipate => lysine
  Shikimate metabolism       EPM0001 Vitamin K biosynthesis, shikimate => menaquinone
          EPM0002 DHNA biosynthesis, shikimate => 1,4-dihydroxy-2-naphthoic acid
  (Others)       M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate
  Chorismate metabolism       M00023 Tryptophan biosynthesis, chorismate => tryptophan
          M00024 Phenylalanine biosynthesis, chorismate => phenylalanine
          M00025 Tyrosine biosynthesis, chorismate => tyrosine
          M00116 Menaquinone biosynthesis, chorismate => menaquinone
          M00117 Ubiquinone biosynthesis, prokaryotes, chorismate => ubiquinone
          M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone
  (Others)       M00040 Tyrosine biosynthesis, prephanate => pretyrosine => tyrosine
  Fatty acid metabolism Saturated fatty acid metabolism Hexadecanoyl-CoA metabolism   M00087 beta-Oxidation
          M00094 Ceramide biosynthesis
          M00099 Sphingosine biosynthesis
      (Others)   M00013 Malonate semialdehyde pathway, propanoyl-CoA => Acetyl-CoA
          M00086 beta-Oxidation, acyl-CoA synthesis
          EPM0053 butyrate biosynthesis (via butyryl-phosphate)
    Unsaturated fatty acid metabolism     M00113 Jasmonic acid biosynthesis
          EPM0059 Linoleic acid metabolism, linoleic acid => vaccenic acid
  Lipid metabolism Sphingolipids metabolism Ceramide metabolism   M00066 Lactosylceramide biosynthesis
          M00067 Cerebroside and sulfatide biosynthesis
    Glycerophospholipids metabolism     M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC
          M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE
          M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
    (Others)     M00098 Acylglycerol degradation
  (Others)       M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE
          M00100 Sphingosine degradation
          M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol
          M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate
  Pyruvate metabolism       M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
          M00307 Pyruvate oxidation, pyruvate => acetyl-CoA
          M00535 Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
  Phosphoenolpyruvate metabolism C4-dicarboxylic acid cycle     M00170 C4-dicarboxylic acid cycle, phosphoenolpyruvate carboxykinase type
          M00171 C4-dicarboxylic acid cycle, NAD - malic enzyme type
          M00172 C4-dicarboxylic acid cycle, NADP - malic enzyme type
    (Others)     M00168 CAM (Crassulacean acid metabolism), dark
          M00169 CAM (Crassulacean acid metabolism), light
          M00358 Coenzyme M biosynthesis
  Acetyl-CoA metabolism       M00009 Citrate cycle (TCA cycle, Krebs cycle)
          M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
          M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
          M00012 Glyoxylate cycle
          M00095 C5 isoprenoid biosynthesis, mevalonate pathway
          M00173 Reductive citrate cycle (Arnon-Buchanan cycle)
          M00082 Fatty acid biosynthesis, initiation
          M00083 Fatty acid biosynthesis, elongation
          M00415 Fatty acid biosynthesis, elongation, endoplasmic reticulum
          M00085 Fatty acid biosynthesis, elongation, mitochondria
          M00088 Ketone body biosynthesis, acetyl-CoA => acetoacetate/3-hydroxybutyrate/acetone
          M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
          M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate
          M00373 Ethylmalonyl pathway
          M00374 Dicarboxylate-hydroxybutyrate cycle
          M00375 Hydroxypropionate-hydroxybutylate cycle
          M00376 3-Hydroxypropionate bi-cycle
  Nucleotide metabolism Purine metabolism     M00546 Purine degradation, xanthine => urea
    Pyrimidine metabolism     M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate
    GTP metabolism     M00125 Riboflavin biosynthesis, GTP => riboflavin/FMN/FAD
          M00126 Tetrahydrofolate biosynthesis, GTP => THF
    CDP/CTP metabolism     M00053 Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP
    Inosine monophosphate utilization     M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP
          M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP
    UMP metabolism     M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP
    (Others)     M00127 Thiamine biosynthesis, AIR => thiamine-P/thiamine-2P
          EPM0099 Purine deoxyribonucleosides degradation, 2'-deoxyadenosine  / 2'-deoxyinosine => 2-deoxy-alpha-D-ribose 1-phosphate
  Putrescine metabolism       M00135 GABA biosynthesis, eukaryotes, putrescine => GABA
          M00136 GABA biosynthesis, prokaryotes, putrescine => GABA
  Choline metabolism       M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC
          M00555 Betaine biosynthesis, choline => betaine
          EPM0076 Phosphatidylcholine metabolism, choline =>  trimethyl amine
  Tetrahydrofolate metabolism       M00140 C1-unit interconversion, prokaryotes
          M00141 C1-unit interconversion, eukaryotes
  Nitrosoamine degradation       EPM0122 Nitrosoamine degradation, DMN -> DMA
          EPM0123 Nitrosoamine degradation, DPN -> nitrite
  Acetate metabolism       EPM0052 butyrate biosynthesis (utilizing acetate)
  Methanogenesis       M00356 Methanogenesis, methanol => methane
          M00357 Methanogenesis, acetate => methane
          M00563 Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
          M00567 Methanogenesis, CO2 => methane
          EPM0006 Methanogenic pathway
  others       M00120 Coenzyme A biosynthesis, pantothenate => CoA
          M00139 -
          EPM0014 Sinigrin degradation
          EPM0015 sodium cyclamate metabolism, Cyclohexylsulfamate => Cyclohexylamine
          EPM0040 hippuric acid production, quinic acid => hippuric acid
Toxin metabolism         EPM0070 Cycasin metabolism, cycasin => methylazoxymethanol
          EPM0072 T-2 Toxin transformation, T-2 toxin => deepoxy T-2 triol
others CO2 metabolism       M00377 Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway)
          M00422 Acetyl-CoA pathway, CO2 => acetyl-CoA
  Nitrate metabolism       M00529 Denitrification, nitrate => nitrogen
          M00530 Dissimilatory nitrate reduction, nitrate => ammonia
          M00531 Assimilatory nitrate reduction, nitrate => ammonia
  (Others)       M00175 Nitrogen fixation, nitrogen => ammonia
          M00528 Nitrification, ammonia => nitrite
  Corrinoide metabolism       M00122 Cobalamin biosynthesis, cobinamide => cobalamin
  Pimeloyl-Coa/ACP metabolism       M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin
          M00573 Biotin biosynthesis, BioI pathway, long-chain-acyl-ACP => pimeloyl-ACP => biotin
          M00577 Biotin biosynthesis, BioW pathway, pimelate => pimeloyl-CoA => biotin
  (Others)       M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP
  Formaldehyde metabolism       M00344 Formaldehyde assimilation, xylulose monophosphate pathway
          M00345 Formaldehyde assimilation, ribulose monophosphate pathway
  (Others)       M00174 Methane oxidation, methanotroph, methane => formaldehyde
          M00176 Assimilatory sulfate reduction, sulfate => H2S
          M00378 F420 biosynthesis
          EPM0011 ethanol metabolism, ethanol => acetate
          EPM0012 Arsenic methylation